Search Results for: carcinoid syndrome

Somatostatin analogues

October 17, 2015

Are drugs such as octreotide and lanreotide that copy or mimic the action of somatostatin. They are also known as biotherapy. Somatostatin is a substance produced naturally in many parts of the body. It can stop the over production of hormones, causing…

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Selective Serotonin Reuptake Inhibitor (SSRI)

October 17, 2015

A popular class of antidepressant medication that typically decreases anxiety as well as depression (Prozac, Zoloft, Paxil). It acts by blocking the reuptake of serotonin. It is contraindicated in patients with carcinoid syndrome as it may preciptate…

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Sandostatin ® s.c., Sandostatin LAR® Depot (generic name octreotide acetate)

October 17, 2015

A somatostatin analogue, anti-hormone drug that is indicated for treatment in patients with metastatic carcinoid tumors, carcinoid syndrome and related NETs. It is given by sub cutaneously injection 2-4 times per day, and then the injection may be…

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Interferon

October 17, 2015

A naturally produced chemical released by the body in response to viral infections. Interferon can be artificially produced and used as a form of immunotherapy.A biological response modifier (a substance that can improve the body’s natural …

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Hot flash

October 17, 2015

A sudden, temporary onset of body warmth, flushing, and sweating (often associated with menopause). Not to be confused with flushing caused by carcinoid syndrome. (See flushing)…

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Epinephrine

October 17, 2015

Epinephrine is a naturally occurring hormone, also called adrenaline. It is one of two chemicals (the other is norepinephrine) released by the adrenal gland. Epinephrine increases the speed and force of heartbeats and thereby the work that can be done…

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Should I take niacin or niacinamide if 50 mg of niacin in my multi-vitamin caused me to flush within 1 to 2 hours of taking it?

October 17, 2015

Low doses of niacin (25 mg twice a day after meals) should not cause flushing, is sufficient, and is easily metabolized.  However, if you are hypersensitive, you can take ½ (81 mg) of a pediatric aspirin just before each niacin dose to prevent flushing or…

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What about other vitamin or dietary supplements?

October 17, 2015

I do endorse a multiple vitamin supplement and all patients with carcinoid syndrome should take low doses of niacin to prevent subclinical pellagra.…

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Is subcutaneous rescue octreotide indicated for dentistry?

October 17, 2015

In general all carcinoid syndrome patients should be given a booster dose of regular octreotide just prior to any anesthesia, surgery or dentistry.…

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Does the body build up a tolerance to Sandostatin LAR or IR over time so that it becomes less effective?

October 17, 2015

Usually NOT. It may infrequently produce antibodies that make it less effective, but this is in only a very small minority of cases. In some other cases it becomes less effective AT THE SAME DOSAGE because the tumors are growing. In most cases it is better…

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