Are there medications to avoid with dentistry?
All adrenaline (epinephrine) containing drugs must be avoided.…READ MORE
What is the effect of chemotherapy on carcinoid?
Chemotherapy is effective in 1/3 of midgut carcinoids and in a larger percentage of foregut (including pancreatic) carcinoids. It is also more effective in atypical carcinoids. Sandostatin in large doses (300 mcg every 6-8 hours) often controls symptoms…READ MORE
Does the body build up a tolerance to Sandostatin LAR or IR over time so that it becomes less effective?
Usually NOT. It may infrequently produce antibodies that make it less effective, but this is in only a very small minority of cases. In some other cases it becomes less effective AT THE SAME DOSAGE because the tumors are growing. In most cases it is better…READ MORE
Does Sandostatin cause carcinoid tumors to reduce production of their chemicals?
Sandostatin works in both ways.…READ MORE
My doctor feels cytotoxic treatment, after embolization, is pointless — what is your viewpoint?
Cytoxic treatment is NOT pointless, especially after embolization treatment. It prolongs life. See article by Moertel et. al. The management of patients with advanced carcinoid tumors and islet cell carcinomas.
How does the pump work with Sandostatin?
The pump is a device in wide use for diabetics who need insulin. It usually is an elastic plastic ball which is filled with medicine under pressure and as it contracts very slowly it squeezes out the medicine slowly at a steady rate into a small plastic catheter…READ MORE
What are the side effects of Sandostatin?
15% of carcinoid patients cannot tolerate Sandostatin and it will not help them. There are additional medicines available which sometimes can make the Sandostatin tolerable or work. However, in some cases it must be abandoned and other forms of treatment…READ MORE
In your editorial section on treatment, liver transplant “in very special selected cases” is mentioned; what are those cases?
The reported world experience with liver transplant for carcinoid indicates that the outcome in general is as good but no better than that resulting from the best combination of multimodality treatment ( i.e. Octreotide/Sandostatin, Hepatic Artery…READ MORE