Medical Reviews
Year 2018
First-in-human trial of 64Cu-SARTATE PET imaging of patients with neuroendocrine tumours demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy
Hicks RJ1, Jackson P2, Kong G2, Ware RE2, Hofman MS2, Pattison DA3, Akhurst T2, Drummond E2, Roselt P2, Callahan J2, Price R4, Jeffery C5, Hong E2, Noonan W6, Herschtal A2, Hicks LJ7, Harris M8, Hedt A5, Paterson BM9, Donnelly P10.
J Nucl Med. 2018 Nov 15 (epub ahead of print)
READ MOREPre-existing Symptoms and Healthcare Utilization Prior to Diagnosis of Neuroendocrine Tumors: A SEER-Medicare Database Study.
Shen C1,2, Dasari A3, Xu Y1, Zhou S2, Gu D1, Chu Y1, Halperin DM3, Shih YT1, Yao JC4.
Sci Rep. 2018 Nov 15; 8(1)
READ MORERelationship Between Symptoms and Health-Related Quality-of-Life Benefits in Patients With Carcinoid Syndrome: Post Hoc Analyses From TELESTAR.
Cella D1, Beaumont JL2, Hudgens S3, Marteau F4, Feuilly M4, Houchard A4, Lapuerta P5, Ramage J6, Pavel M7, Hörsch D8, Kulke MH9.
Clin Ther. 2018 Nov 23 (epub ahead of print)
READ MORECurrent treatment strategies for patients with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
Inbal Uri and Simona Grozinsky-Glasberg
Clin Diabetes Endocrinol. 2018 July 11; 4(16)
READ MOREHealth-Related Quality of Life in Patients With Progressive Midgut Neuroendocrine Tumors Treated With 177Lu-Dotatate in the Phase III NETTER-1 Trial
Strosberg J1, Wolin E1, Chasen B1, Kulke M1, Bushnell D1, Caplin M1, Baum RP1, Kunz P1, Hobday T1, Hendifar A1, Oberg K1, Sierra ML1, Thevenet T1, Margalet I1, Ruszniewski P1, Krenning E1; NETTER-1 Study Group.
J Clin Oncol. 2018 Sept; 36(25): 2578-2584
READ MOREYear 2017
Appropriate Use Criteria for Somatostatin Receptor PET Imaging in Neuroendocrine Tumors
Hope TA1, Bergsland E2, Bozkurt MF3, Graham MM1, Heaney AP4, Herrmann K3, Howe JR5, Kulke MH2, Kunz PL2, Mailman J1, May L6, Metz DC5, Millo C1, O’Dorisio S1, Reidy-Lagunes DL2, Soulen MC7, Strosberg JR2
J Nucl Med. 2017 Oct
READ MORE68Ga-DOTATOC Imaging of Neuroendocrine Tumors: A Systematic Review and Metaanalysis
Graham MM1, Gu X2, Ginader T3, Breheny P3, Sunderland JJ4
The Journal of Nuclear Medicine. 2017 September; 58(9): 1452-1458
READ MOREThe Surgical Management of Small Bowel Neuroendocrine Tumors: Consensus Guidelines of the North American Neuroendocrine Tumor Society
Howe JR, Cardona K, Fraker DL, Kebebew E, Untch BR, Wang YZ, Law CH, Liu EH, Kim MK, Menda Y, Morse BG, Bergsland EK, Strosberg JR, Nakakura EK, Pommier RF
Pancreas. 2017 July; 46(6): 715-731
READ MOREThe North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Midgut Neuroendocrine Tumors
Strosberg JR, Halfdanarson TR, Bellizzi AM, Chan JA, Dillon JS, Heaney AP, Kunz PL, O’Dorisio TM, Salem R, Segelov E, Howe JR, Pommier RF, Brendtro K, Bashir MA, Singh S, Soulen MC, Tang L, Zacks JS, Yao JC, Bergsland EK
Pancreas. 2017 July; 46(6): 707-714
READ MOREPatient-Reported Experience of Diagnosis, Management, and Burden of Neuroendocrine Tumors: Results from a Large Patient Survey in the United States
Wolin EM, Leyden, J, Goldstein G, Kolarova T, Hollander R, Warner RRP
Pancreas. 2017 May/June; 46(5): 639-647
READ MORETrends in the Incidence, Prevalence, and Survival Outcomes in Patients with Neuroendocrine Tumors in the United States
Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, Shih T, Yao JC
JAMA Oncology. 2017 April [epub ahead of print]
READ MOREClinical, pathological and demographic factors associated with development of recurrences after surgical resection in elderly patients with neuroendocrine tumors
Shen C, Dasari A, Chu Y, Halperin DM, Zhou S, Xu Y, Shih Y, Yao JC
Ann Oncol. 2017 April 21 [epub ahead of print]
READ MOREPrognostic factors in ectopic Cushing’s syndrome due to neuroendocrine tumors: a multicenter study
Davi’ MV1, Cosaro E2, Piacentini S3, Reimondo G4, Albiger N5, Arnaldi G6, Faggiano A7, Mantovani G8, Fazio N9, Piovesan A10, Arvat E10, Grimaldi F11, Canu L12, Mannelli M12, Ambrogio AG13,14, Pecori Giraldi F13,14, Martini C15, Lania A16, Albertelli M17, Ferone D18, Zatelli MC19, Campana D20, Colao A21, Scaroni C5, Terzolo M4, De Marinis L3, Cingarlini S22, Micciolo R23, Francia G2.
Eur J Endocrinol. 2017 Apr; 176(4): 451-459
READ MOREDiagnosing and Managing Carcinoid Heart Disease in Patients With Neuroendocrine Tumors: An Expert Statement
Davar J1, Connolly HM2, Caplin ME3, Pavel M4, Zacks J5, Bhattacharyya S6, Cuthbertson DJ7, Dobson R8, Grozinsky-Glasberg S9, Steeds RP10, Dreyfus G11, Pellikka PA2, Toumpanakis C12
J Am Coll Cardiol. 2017 March ; 69(10): 1288-1304
READ MOREComprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma
Fishbein L, Leshchiner I, Walter V, Danilova L, Robertson AG, Johnson AR, Lichtenberg TM, Murray BA, Ghayee HK, Else T, Ling S, Jefferys SR, de Cubas AA, Wenz B, Korpershoek E, Amelio AL, Makowski L, Rathmell WK, Gimenez-Roqueplo AP, Giordano TJ, Asa SL, Tischler AS; Cancer Genome Atlas Research Network, Pacak K, Nathanson KL, Wilkerson MD
Cancer Cell. 2017 Feb; 1(001): pii: S1535-6108(17)300001-6
READ MOREPhase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors
Strosberg J, El-Haddad G, Wolin E, Hendifar A, Yao J, Chasen B, Mittra E, Kunz PL, Kulke MH, Jacene H, Bushnell D, O’Dorisio TM, Baum RP, Kulkarni HR, Caplin M, Lebtahi R, Hobday T, Delpassand E, Van Cutsem E, Benson A, Srirajaskanthan R, Pavel M, Mora J, Berlin J, Grande E, Reed N, Seregni E, Öberg K, Lopera Sierra M, Santoro P, Thevenet T, Erion JL, Ruszniewski, Kwekkeboom D, Krenning E; NETTER-1 Trial Investigators
N Engl J Med. 2017 January; 376(2): 125-135
READ MOREYear 2016
Telotristat Ethyl, a Tryptophan Hydroxylase Inhibitor for the Treatment of Carcinoid Syndrome
Kulke MH1, Hörsch D1, Caplin ME1, Anthony LB1, Bergsland E1, Öberg K1, Welin S1, Warner RR1, Lombard-Bohas C1, Kunz PL1, Grande E1, Valle JW1, Fleming D1, Lapuerta P1, Banks P1, Jackson S1, Zambrowicz B1, Sands AT1, Pavel M1
Journal of Clinical Oncoloyg. 2016 October
READ MOREAssociation Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors
Qian ZR1, Li T, Ter-Minassian M, Yang J, Chan JA, Brais LK, Masugi Y, Thiaglingam A, Brooks N, Nishihara R, Bonnemarie M, Masuda A, Inamura K, Kim SA, Mima K, Sukawa Y, Dou R, Lin X, Christiani DC, Schmidlin F, Fuchs CS, Mahmood U, Ogino S, Kulke MH
Pancreas. 2016 Sept
READ MOREDevelopment of Effective Prophylaxis against Intraoperative Carcinoid Crisis
Woltering EA1, Wright AE2, Stevens MA3, Wang YZ4, Boudreaux JP5, Mamikunian G6, Riopelle JM7, Kaye AD8
J Clin Anesth. 2016 Aug; 32: 189-93
READ MOREPatient-Reported Burden of a Neuroendocrine Tumor (NET) Diagnosis: Results from the First Global Survey of Patients with NETs
Singh S, Granberg D, Wolin E, Warner R, Sissons M, Kolarova T, Goldstein G, Pavel M, Oberg K, Leyden J
Journal of Global Oncology. 2016 June : 1-11
READ MOREDiagnosis and Management of Gastrointestinal Neuroendocrine Tumors: An Evidence-Based Canadian Consensus
Singh S1, Asa SL2, Dey C3, Kennecke H4, Laidley D5, Law C6, Asmis T7, Chan D8, Ezzat S9, Goodwin R10, Mete O11, Pasieka J12, Rivera J13, Wong R14, Segelov E15, Rayson D16
Cancer Treat Rev. 2016 June; 47: 32-45
READ MOREDifferential Protein Expression in Small Intestinal Neuroendocrine Tumors and Liver Metastases
Kim MK1, Ye F, Wang D, Cui M, Ward SC, Warner RR, Roayaie S, Shafir M, Schwartz M, Zhang D, Itzkowitz S.
Pancreas. 2016 April; 45(4): 528-532
READ MOREElevated Plasma Pancreastatin, but Not Chromogranin A, Predicts Survival in Neuroendocrine Tumors of the Duodenum
Woltering EA1, Beyer DT2, Thiagarajan R3, Ramirez RA4, Wang YZ3, Ricks MJ4, Boudreaux JP3
J Am Coll Surg. 2016 April; 222(4): 534-42
READ MORESomatostatin Analogues in Neuroendocrine Tumors
Kulke, MH
J Natl Compr Canc Netw. 2016 March; 14(3): 241-242
READ MORENeuroendocrine tumor biomarkers: From monoanalytes to transcripts and algorithms
Modlin IM1, Bodei L2, Kidd M3.
Best Practice & Research Clinical Endocrinology & Metabolism. 2016 January; 30(1): 59-77
READ MOREConsensus Guidelines for High Grade Gastro-Entero-Pancreatic (GEP) Neuroendocrine Tumours and Neuroendocrine Carcinomas (NEC)
Garcia-Carbonero R1, Sorbye H, Baudin E, Raymond E, Wiedenmann B, Niederle B, Sedlackova E, Toumpanakis C, Anlauf M, Cwikla J, Caplin M, O’Toole D, Perren A; all other Vienna Consensus Conference participants.
Neuroendocrinology. 2016 January {Epub ahead of print}
READ MOREConsensus Guidelines Update for Colorectal Neuroendocrine Neoplasms (NEN)
Ramage J1, De Herder WW, Delle Fave GF, Ferolla P, Ferone D, Ito T, Ruszniewski P, Sundin A, Weber W, Zheng-Pei Z, Taal B, Pascher A; all other Vienna Consensus Conference participants.
Neuroendocrinology. 2016 January {Epub ahead of print}
READ MOREConsensus Guidelines for Neuroendocrine Neoplasms of the Appendix (Excluding Goblet Cell Carcinomas)
Pape UF1, Niederle B, Costa F, Gross D, Kelestimur F, Kianmanesh R, Knigge U, Öberg K, Pavel M, Perren A, Toumpanakis C, O’Connor J, Krenning E, Reed N, O’Toole D; all other Vienna Consensus Conference participants.
Neuroendocrinology. 2016 January {Epub ahead of print}
READ MOREConsensus Guidelines Update for the Management of Distant Metastatic Disease of Intestinal, Pancreatic, Bronchial Neuroendocrine Neoplasms (NEN) and NEN of Unknown Primary Site
Pavel M1, O’Toole D, Costa F, Capdevila J, Gross D, Kianmanesh R, Krenning E, Knigge U, Salazar R, Pape UF, Öberg K; all other Vienna Consensus Conference participants
Neuroendocrinology. 2016 January {Epub ahead of print}
READ MOREYear 2015
Elevated Serum Pancreastatin Is an Indicator of Hepatic Metastasis in Patients With Small Bowel Neuroendocrine Tumors
Khan TM1, Garg M, Warner RR, Uhr JH, Divino CM.
Pancreas. 2015 Dec [epub ahead of print]
READ MORESurgical Treatment as a Principle for Patients with High-Grade Pancreatic Neuroendocrine Carcinoma: A Nordic Multicenter Comparative Study
Haugvik SP1,2, Janson ET3, Österlund P4, Langer SW5, Falk RS6, Labori KJ7, Vestermark LW8, Grønbæk H9, Gladhaug IP7,10, Sorbye H11
Ann Surg Oncol. 2015 Dec [epub ahead of print]
READ MOREGastrointestinal Carcinoid Tumors (PDQ®): Treatment for Health Professionals
From the National Cancer Institute
READ MORENew and Emerging Treatment Options for Gastroenteropancreatic Neuroendocrine Tumors
Phan AT, Kunz PL1, Reidy-Lagunes DL
Clin Adv Hematol Oncol. 2015 May; 13(5 Suppl 5): 1-18; quiz 1 p following 18
READ MORENeuroendocrine tumors, version 1.2015
Kulke MH, Shah MH, Benson AB 3rd, Bergsland E, Berlin JD, Blaszkowsky LS, Emerson L, Engstrom PF, Fanta P, Giordano T, Goldner WS, Halfdanarson TR, Heslin MJ, Kandeel F, Kunz PL, Kuvshinoff BW 2nd, Lieu C, Moley JF, Munene G, Pillarisetty VG, Saltz L, Sosa JA, Strosberg JR, Vauthey JN, Wolfgang C, Yao JC, Burns J, Freedman-Cass D; National comprehensive cancer network.
J Natl Compr Canc Netw. 2015 Jan 1; 13(1): 78-108
READ MOREYear 2014
NCCN Clinical Practice Guidelines In Oncology, Neuroendocrine Tumors
National Comprehensive Cancer Network (NCCN). 2014 November: 1-108
READ MOREMolecular pathology and genetics of gastrointestinal neuroendocrine tumors
Lewis MA, Yao JC
Curr Opin Endocrinol Diabetes Obes . 2014; 21(000-000): e-published ahead of print
READ MOREProspective of 68Ga-Radiopharmaceutical Development
Velikyan, Irina
Theranostics. 2014; 4(1): 47-80. doi: 10.7150/thno.7447
READ MORELanreotide in Metastatic Enteropancreatic Neuroendocrine Tumors
Caplin ME, Pavel M, Ruszniewski P.
N Engl J Med. 2014 July; 371(16): 224-233
READ MORERecommendations for management of patients with neuroendocrine liver metastases
Frilling A1, Modlin IM2, Kidd M3, Russell C4, Breitenstein S5, Salem R6, Kwekkeboom D7, Lau WY8, Klersy C9, Vilgrain V10, Davidson B4, Siegler M11, Caplin M12, Solcia E9, Schilsky R13; Working Group on Neuroendocrine Liver Metastases.
Lancet Oncol. 2014 Jan; 15(1): e8-e21
READ MOREYear 2013
Everolimus Plus Octreotide Long-Acting Repeatable in Patients with Colorectal Neuroendocrine Tumors: A Subgroup Analysis of the Phase III RADIANT-2 Study
Castellano D, Bajetta E, Panneerselvam A, Saletan S, Kocha W, O’Dorisio T, Anthony LB, Hobday T
The Oncolgist. 2013; 18: 46-53
READ MOREPractical Guide to Supportive Care of Patients With Functional Neuroendocrine Tumors
Anthony, Lowell B.
Semin Oncol. 2013; 40: 45-55
READ MOREThe Genomic Landscape of Small Intestine Neuroendocrine Tumors
Banck MS, Kanwar R, Kulkarni AA, Boora GK, Metge F, Kipp BR, Zhang L, Thorland EC, Minn KT, Tentu R, Eckloff BW, Wieben ED, Wu Y, Cunningham JM, Nagorney DM, Gilbert JA, Ames MM, Beutler AS
J Clin Invest. 2013 May 15
READ MOREThe Identification of Gut Neuroendocrine Tumor Disease by Multiple Synchronous Transcript Analysis in Blood
Irvin M. Modlin, Ignat Drozdov, Mark Kidd
PLOS One. 2013 May
READ MORETargeted Therapies in Neuroendocrine Tumors (NET): Clinical Trial Challenges and Lessons Learned
Yao JC, Reidy Lagunes D, Kulke MH
The Oncologist. 2013 April 24
READ MOREUnited States-based practice patterns and resource utilization in advanced neuroendocrine tumor treatment.
trosberg J, Casciano R, Stern L, Parikh R, Chulikavit M, Willet J, Liu Z, Wang X, Grzegorzewski KJ
World J Gastroenterolo. 2013 April 21; 19(15): 2348-2354
READ MOREGenetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options
Vicha A, Musil Z, Pacak K
Curr Opin Endocrinol Diabetes Obes. 2013 Mar 11
READ MOREAdvances in Pulmonary Neuroendocrine Tumor Management
Kjell Oberg
Advances in Pulmonary Neuroendocrine Tumor Management. 2013 March: doi: 10.2217/9781780841625 eISBN (PDF): 978-1-78084-162-5
READ MOREUpdate on the management of unusual neuroendocrine tumors: pheochromocytoma and paraganglioma, medullary thyroid cancer and adrenocortical carcinoma
Strosberg, JR
Semin Oncol. 2013 February; 40(1): 120-33
READ MOREAre Neuroendocrine Tumors Going Mainstream?
Kulke, M
JCO. 2013 Feb 1; 31(4): 404-405 [Epub ahead of print]
READ MOREPractical Guidance on Peptide Receptor Radionuclide Therapy (PRRNT) for Neuroendocrine Tumours
International Atomic Energy Agency
IAEA Human Health Series. 2013
READ MOREYear 2012
Clinical Practice Guidelines for Multiple Endocrine Neoplasia Type 1 (MEN1)
Thakker RV, Newey PJ, Walls GV, Bilezikian J, Dralle H, Ebeling PR, Melmed S, Sakurai A, Tonelli F, Brandi ML
J Clin Endocrinol Metab. 2012 Jun 20; [Epub ahead of print]
READ MOREThe management of neuroendocrine tumours: current and future medical therapy options.
Oberg, KE
Clin Oncol (R Coll Radiol). 2012 May 24; 24(4): 282-93. Epub 2011 Sep 9.
READ MOREManagement of neuroendocrine tumors in children, adolescents, and young adults
Howell D, O’Dorisio MS
J Pediatr Hematol Oncol. 2012 May; 34(Supple 2): S64-68
READ MOREThe risk of metachronous cancers in patients with small intestinal carcinoid tumors: a US population-based study.
Amin S, Warner RR, Itzkowitz SH, Kim MK
Endocr Relat Cancer. 2012 Mar 27; [Epub ahead of print]
READ MOREYear 2011
Current Scientific Rationale for the Use of Somatostatin Analogs and mTOR Inhibitors in Neuroendocrine Tumor Therapy.
Bousquet C, Lasfargues C, Chalabi M, Moatassim Billah S, Susini C, Vezzosi D, Caron P, Pyronnet S
J Clin Endocrinol Metab. 2011 Dec 14; [Epub ahead of print]
READ MOREManagement of Neuroendocrine Tumors of Unknown Origin
Polish A, Vergo MT, Agulnik M
J Natl Compr Canc Netw. 2011; 9(12): 1397-1403
READ MORETreatment of liver metastases in patients with neuroendocrine tumors: a comprehensive review.
Harring TR, Nguyen NT, Goss JA, O’Mahony CA
Int J Hepatol. 2011 Oct 13; 2011;2011:154541(doi: 10.4061/2011/154541)
READ MOREA Review of Systemic and Liver-Directed Therapies for Metastatic Neuroendocrine Tumors of the Gastroenteropancreatic Tract
Strosberg JR, Cheema A, Kvols, LK
Cancer Control. 2011 April; 18(2): 127-37
READ MOREYear 2010
Targeted Radionuclide Therapy for Neuroendocrine Tumours: Principles and Application
Maralyn R. Drucea Val Lewingtonb Ashley B. Grossman
Neuroendocrinology. 2010; 91(1): 1-15. Epub 2009 Jul 7.
READ MORENew Medical Strategies for Midgut Carcinoids
Ola Nilsson1, Yvonne Arvidsson1, Viktor Johanson2, Eva Forssell-Aronsson3 and Håkan Ahlman2,*
Departments of Pathology1, Surgery2 and Radiation Physics3 at the Sahlgrenska Academy, University of Gothenburg, Gothenburg,
Sweden
Anti-Cancer Agents in Medicinal Chemistry. 2010; 10: 250-269
READ MORECirculating Biomarkers in Neuroendocrine Tumors of the Enteropancreatic Tract: Application to Diagnosis, Monitoring Disease, and as Prognostic Indicators
Ardill JES, O’Dorisio TM
Endocrinol Metab Clin N Am 39 . 2010: 777-790
READ MOREParaneoplastic syndromes secondary to neuroendocrine tumours
Kaltsas G, Andoulakis II, de Herder WW, Grossman, AB
Endocrine-Related Cancer. 2010 Jul 28; 17(3): R173-R193 Print 2010 Sept
READ MOREMolecular markers for novel therapies in neuroendocrine (carcinoid) tumors.
Gilbert JA, Adhikari LJ, Lloyd RV, Rubin J, Haluska P, Carboni JM, Gottardis MM, Ames MM
Endocr Relat Cancer. 2010 Jun 25; 17(3): 623-36. Print 2010
READ MOREFunctional Imaging of NeuroendocrineTumors: A Head-to-Head Comparison of Somatostatin Receptor Scintigraphy, 123I-MIBG Scintigraphy, and 18F-FDG PET
Tina Binderup, Ulrich Knigge, Annika Loft, Jann Mortensen, Andreas Pfeifer, Birgitte Federspiel, Carsten Palnaes Hansen, Liselotte Højgaard, and Andreas Kjaer
Authors’ Affiliations: Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen, Denmark; Cluster for Molecular Imaging, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
J Nucl Med. 2010 May; 51: 704–712
READ MOREIdentification of a Novel Raf-1 Pathway Activator that Inhibits Gastrointestinal Carcinoid Cell Growth
Mackenzie R. Cook, Scott N. Pinchot, Renata Jaskula-Sztul, Jie Luo, Muthusamy Kunnimalaiyaan, and Herbert Chen
Authors’ Affiliations: Endocrine Surgery Research Laboratory, University of Wisconsin, and the University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
Mol Cancer Ther. 2010 Jan 26; 9(2): 429–37
READ MOREYear 2009
Biochemical testing for neuroendocrine tumors
Vinik AI, Silva MP, Woltering EA, Go VL, Warner R, Caplin M.
Eastern Virginia Medical School, Strelitz Diabetes Research Center, Norfolk, VA 23510, USA
Pancreas. 2009 Nov; 38(8): 876-89
READ MORENeuroendocrine Tumors: A Comprehensive Guide to Diagnosis and Management, Fourth Edition (PDF file, full text, 259 pages)
Gregg Mamikunian, MS; Aaron I. Vinik, MD, PhD, FCP, MACP; Thomas M. O’Dorisio, MD; Eugene A. Woltering, MD, FACS; Vay Liang W. (Bill) Go, MD
Inter Science Institute. 2009
READ MOREENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Echocardiography
Ursula Plöckingera Björn Gustafssonb Diana Ivanc Waldemar Szpakd
Joseph Davaree and all other Mallorca Consensus Conference participants
a Department of Hepatology and Gastroenterology, Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Berlin, Germany;
b Medisinsk avd Gastroseksjon, St Olavs Hospital HF, Trondheim, Norway;
c Endocrinology and Diabetology, Klinikum der Philipps-Universität, Marburg, Germany;
d Westville Hospital, Amanzimototi, Mayville, South Africa;
e Department of Cardiology, Royal Free Hospital, London, UK
Neuroendocrinology. 2009; 90: 190-193
READ MORESunitinib paves the way for targeted therapies in neuroendocrine tumors
Raymond E, Faivre S, Hammel P, Ruszniewski P
Department of Medical Oncology and Gastroenterology,
Beaujon University Hospital, Clichy, France,
eric.raymond@bjn.aphp.fr
Targeted Oncology . 2009; 4: 253-254
READ MOREMolecular target therapy for gastroenteropancreatic endocrine tumours: Biological rationale and clinical perspectives
Gabriele Capursoaa,1, Nicola Faziobb,1, Stefano Festaaa, Francesco Panzutoaa, Filippo De Braudbb, Gianfranco Delle Faveaaa,*
a Digestive and Liver Disease Unit, S. Andrea Hospital, II Medical School, University “La Sapienza”, Via Di Grottarossa 1035-1039, 00189, Rome, Italy
b Unit of Clinical Pharmacology and New Drugs, European Institute of Oncology, Milan, Italy
Critical Reviews in Oncology/Hematology. 2009; 72: 110-124
READ MOREPlacebo-Controlled, Double-Blind, Prospective, Randomized Study on the Effect of Octreotide LAR in the Control of Tumor Growth in Patients With Metastatic Neuroendocrine Midgut Tumors: A Report From the PROMID Study Group
Anja Rinke, Hans-Helge Müller, Carmen Schade-Brittinger, Klaus-Jochen Klose, Peter Barth, Matthias Wied, Christina Mayer, Behnaz Aminossadati, Ulrich-Frank Pape, Michael Bläker, Jan Harder, Christian Arnold, Thomas Gress, and Rudolf Arnold
Journal of Clinical Oncology. 2009 Oct 1; 27(28): 4656-63
READ MORELong-term results of patients with malignant carcinoid syndrome receiving octreotide LAR
Toumpanakis C, Garland J, Marelli L, Srirajaskanthan R, Soh J, Davies P, Buscombe J, Caplin ME.
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK.
Alimentary Pharmacology & Therapeutics Journal. 2009 Oct; 30(7): 733-40. Epub 2009 Jul 2.
READ MOREPancreatic neuroendocrine tumors: presentation, management, and outcomes
Nissen NN, Kim AS, Yu R, Wolin EM, Friedman ML, Lo SK, Wachsman AM, Colquhoun SD
Am Surg. 2009 October; 75(10): 1025-9
READ MOREChromogranin-A and N-Terminal Pro-Brain Natriuretic Peptide: An Excellent Pair of Biomarkers for Diagnostics in Patients with Neuroendocrine Tumor
Catharina M. Korse, Babs G. Taal, Cornelis A. de Groot, Robert H. Bakker, and Johannes M.G. Bonfrer
Journal Clinical Oncology. 2009 Sep 10; 27: 4293-4299
READ MORECorrelation between grade and prognosis in metastatic gastroenteropancreatic neuroendocrine tumors
Strosberg J, Nasir A, Coppola D, Wick M, Kvols L
Hum Pathol. 2009 Sep; 40(9): 1262-8. Epub 2009 Apr 14
READ MORETreatment of metastatic carcinoid tumors with radiolabeled biologic molecules
Bushnell D.
University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.david-bushnell@uiowa.edu
Bushnell D. University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA. david-bushnell@uiowa.edu. 2009 Jul 7; 7(7): 760-4
READ MOREProlonged survival after hepatic artery embolization in patients with midgut carcinoid syndrome
Swärd C, Johanson V, Nieveen van Dijkum E, Jansson S, Nilsson O, Wängberg B, Ahlman H, Kölby L
British Journal of Surgery. 2009 May
READ MOREYear 2008
NCI Carcinoid/NET Summit 2007; Main Conclusions
Irvin M. Modlin , Steven F. Moss , Daniel C. Chung , Robert T . Jensen , Elizabeth Snyderwine
J Natl Cancer Inst.. 2008 Sep 17; 100(18): 1282-1289
READ MOREClinical Value of Monitoring Plasma Octreotide Levels During Chronic Octreotide Long-Acting Repeatable Therapy in Carcinoid Patients
Woltering EA, Salvo VA, O’Dorisio TM, Lyons J 3rd, Li G, Zhou Y, Seward JR, Go VL, Vinik AI, Mamikunian P, Mamikunian G.
Department of Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA. ewolte@lsuhsc.edu
Pancreas. 2008 Jul; 37(1): 94-100
READ MOREEarly and Late Results of Valvular Surgery for Carcinoid Heart Disease
Javier G. Castillo, Farzan Filsoufi, Parwis B. Rahmanian, Anelechi Anyanwu, Jerome S. Zacks, Richard R.P. Warner, David H. Adam
Journal of the American College of Cardiology. 2008 April 15; 51(15): 1507-1509
READ MOREBronchopulmonary Carcinoid: Phenotype and Long-term Outcome in a Single-Institution Series of Italian Patients
Massimo Rugge, Matteo Fassan, Roberto Clemente4, Giovanna Rizzardi,
Luciano Giacomelli, Gianmaria Pennelli, Claudia Mescoli1, Daniela Segat, and Federico Rea
Clinical Cancer Research. 2008 Jan 1; 14: 149-154. doi: 10.1158/1078-0432.CCR-07-1631
READ MOREYear 2007
Population-based study of islet cell carcinoma
Yao JC, Eisner MP, Leary C, Dagohoy C, Phan A, Rashid A, Hassan M, Evans DB. Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA. jyao@mdanderson.org
Ann Surg Oncol. 2007 Dec; 14(12): 3492-500. Epub 2007 Sep 26.
READ MOREPeptide receptor radionuclide therapy with (177) Lu-octreotate in patients with foregut carcinoid tumours of bronchial, gastric and thymic origin
van Essen M, Krenning EP, Bakker WH, de Herder WW, van Aken MO, Kwekkeboom DJ
Eur J Nucl Med Mol Imaging . 2007; 34(8): 1219-1227
READ MORETemozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors
Ekeblad S, Eriksson B, Sundin A, Welin S, Granberg D, Kindmark H, Dunder K, Kozlovacki G, Örlefors H, Sigurd M, Öberg K, Janson ET, Skogseid B
Clin Cancer Res. 2007; 13(10): 2986-2991
READ MORETumor Suppressor Role of Notch-1 Signaling in Neuroendocrine Tumors
Muthusamy Kunnimalayaan, Herbert Chen
Endocrine Surgery Research Laboratories, Department of Surgery, The University of Wisconsin, and the University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin, USA
The Oncologist . 2007; 12: 535–542
READ MOREResponse of atypical pulmonary carcinid tumors to chemotherapy. A retrospective study of 37 patients
Guigay J.
Poster presented at the12th World Conference on Lung Cancer, Seoul, Korea, September 2007.
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Valproic Acid Activates Notch-1 Signaling and Regulates the Neuroendocrine Phenotype in Carcinoid Cancer Cells
Greenblatt DY, Vaccaro AM, Jaskula-Sztul R, Ning L, Haymart M, Kunnimalaiyaan M, Chen H
F.A.C.S., H4/750 Clinical Science Center, 600 Highland Avenue, Madison, Wisconsin 53792, USA.
Oncologist. 2007 Aug; 12(8): 942-51
READ MOREChemoembolization and Bland Embolization of Neuroendocrine Tumor Metastases to the Liver (Full text)
Ruutiainen AT, Soulen MC, Tuite CM, Clark TW, Mondschein JI, Stavropoulos SW, Trerotola SO.
Division of Interventional Radiology, University of Pennsylvania, 1 Silverstein, Philadelphia, PA 19104, USA
J Vasc Interv Radiol. 2007 Jul; 18(7): 847-55
READ MOREYear 2006
Over expression of the Notch1 intracellular domain (NICD) inhibits cellular proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells
Muthusamy Kunnimalaiyaan, Abram M. Vaccaro, Mary A. Ndiaye, and Herbert Chen
J. Biol. Chem. 2006 Nov 7: 10.1074/jbc.M603578200
READ MOREENETS 2007 Consensus Guidelines for the Management pf Patients with Digestive Neuroendocrine tumors. Part1 Stomach, Duodenum and Pancreas
Wouter De Herder, Dermot O’Toole, Guido Rindi, Bertram Wiedenmann
Karger Neuro endocrinology . 2006; 84(3): 151-153
READ MOREDiagnosis and Management of Neuroendocrine Tumors
by Rudolph Arnold, M.D., FRCP
8th United European Gastroenterology Week
Liver metastases of neuroendocrine tumors; early reduction of tumour load lead to improved life expectancy (full text)
Liesbeth M Veenendaal1, Inne HM Borel Rinkes1, Cornelis JM Lips2and Richard van Hillegersberg*1, Netherlands.
World Journal of Surgical Oncology. 2006 Jun 26; 4: 35
READ MORETherapeutic Options for Gastrointestinal Carcinoids (Abstract)
Irvin M. Modlin, Igor Latich, Mark Kidd, Michelle Zikusoka, and Geeta Eick
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8062, USA. imodlin@optonline.net
Clin Gastroenterol Hepatol. 2006 May; 4(5): 526-47
READ MORESurgery for Gastrinoma and Insulinoma in MEN 1 (Abstract)
Norton JA, Fang TD, Jensen RT
J Natl Compr Canc Netw. 2006 Feb; 4(2): 148-53
READ MOREYear 2005
Goblet cell carcinoid of the appendix
Payam S Pahlavan1 and Rani Kanthan2
1Department of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany
2Department of Pathology, University of Saskatchewan, Saskatoon, Canada
World Journal of Surgical Oncology. 2005; 3: 36
READ MOREBiochemical assessment of niacin deficiency among carcinoid cancer patients.
Shah GM, Shah RG, Veillette H, Kirkland JB, Pasieka JL, Warner RR
Am J Gastroenterol. 2005 Oct; 100(10): 2307-14
READ MOREComparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors
Wang GG, Yao JC, Worah S, White JA, Luna R, Wu TT, Hamilton SR, Rashid A
Mod Pathol. 2005 Aug; 18(8): 1079-87
READ MOREEnteroendocrine Tumors Other Than Carcinoid: A Review of Clinically Significant Advances
Richard R.P. Warner
Gastrointestinal Division, Department of Medicine
The Mount Sinai School of Medicine, New York, NY
Gastroenterology. 2005 May : 1668-1684
READ MORECurrent Status of Gastrointestinal Carcinoids
Irvin M. Modlin, Mark Kidd, Igor Latich, Michelle N. Zikusoka, and Michael D. Shapiro
Gastric Pathobiology Research Group, GI Surgical Division, Yale University School of Medicine, New Haven, Connecticut Revie
Gastroenterology. 2005 May; 128: 1717-1751
READ MOREA Discussion on the Utility of Various Routes of Administration of Octreotide Acetate
Eugene A. Woltering MD FACS
The James D. Rives Professor of Surgery and Neurosciences
Louisiana State University Health Sciences Center
New Orleans LA 70065
Carcinoid tumor of the appendix in childhood: the experience of two Italian institutions
Dall’Igna P, Ferrari A, Luzzatto C, Bisogno G, Casanova M, Alaggio R, Terenziani M, Cecchetto G
J Pediatr Gastroenterol Nutr. 2005 Feb; 40(2): 216-9
READ MOREMetastatic Carcinoid Tumors: A Clinical Review
Johann M. Zeutenhorst, Babs G. Taal
Oncologist. 2005 Feb; 10(2): 123-31
READ MOREOverview of Results of Peptide Receptor Radionuclide Therapy with 3 Radiolabeled Somatostatin Analogs
Kwekkeboom DJ, Mueller-Brand J, Paganelli G, Anthony LB, Pauwels S, Kvols LK, O’dorisio TM, Valkema R, Bodei L, Chinol M, Maecke HR, Krenning EP
J Nucl Med. 2005 Jan; 46(1): 62S-6S
READ MOREYear 2004
Outcome of patients with pulmonary carcinoid tumors receiving chemotherapy or chemoradiotherapy
Wirth LJ, Carter MR, Jänne PA, Johnson BE
Lung Cancer. 2004; 44: 213-20
READ MOREConsiderations Concerning a Tailored, Individualized Therapeutic Management of Patients with (neuro)Endocrine Tumors of the Gastrointestinal Tract and Pancreas
W W de Herder, E P Krenning, C H J van Eijck 2 and S W J Lamberts
Endocrine-Related Cancer . 2004; 11: 19-34
READ MOREThe American Gastroenterological Association (AGA) Forum (2004)
American Gastroenterological Association
READ MORECarcinoid heart disease : presentation, diagnosis, and management
Fox DJ, Khattar RS
Heart. 2004 Oct; 90(10): 1224-8
READ MORECarcinoid heart disease: presentation, diagnosis, and management
Fox and Khattar
Heart. 2004; 90(10): p. 1224
READ MOREUpdated Population-Based Review of Carcinoid Tumors
By Maggard MA, O’Connell JB, Ko CY.
Anna Surg. 2004 Jul; 240(1): 117-22
READ MOREGastroenteropancreatic Neuroendocrine Tumor Disease: Molecular and Cell Biological Aspects
Edited by Bertram Wiedenmann; Gerhard M. Christofori; Michael Hoecker
Annals of the New York Academy of Sciences . 2004 April; 1014
READ MORECurrent Status of the Diagnosis and Treatment of Hereditary and Sporadic Neuroendocrine Tumors of the Gastroenteropancreatic System
European Neuroendocrine Tumor Society (ENETS), Budapest, March 2004
Neuroendocrinology 80 (suppl) 1 1-140(2004)
Editor B Wiedenmann, Publisher Karger
Access Author and Subject Index
Order information
Pictures from the Budapest conference
Neuroendocrinology . 2004 Mar; 80(1)
READ MOREYear 2003
Carcinoid heart disease: The role of urinary 5-hydroxyindoleacetic acid excretion and plasma levels of atrial natriuretic peptide, transforming growth factor-beta and fibroblast growth factor
Zuetenhorst JM, Bonfrer JM, Korse CM, Bakker R, Van Tinteren H, Taal BG
Cancer . 2003; 97: 1609-1615
READ MORECarcinoid Heart Disease
By Zuetenhorst JM, Taal BG.
N Engl J Med. 2003 Jun 5; 348(23): 2359-61
READ MOREAdditional references regarding treatment of patients with bronchial carcinoids
Provided by
Dan Granberg, MD, PhD, Consultant, Assistant Head of Department
Department of Endocrine Oncology
University Hospital
SE-751 85 Uppsala
Sweden
A 5-Decade Analysis of 13,715 Carcinoid Tumors
By Irving M. Modlin, M.D., Kevin D. Lys, M.D., Mark Kidd, Ph.D.
Cancer. 2003 Feb 15; 97(4): 934-59
READ MOREYear 2002
A Carcinoid Tumor Associated with Chylous Ascites and Elevated Tumor Markers
Warner RR, Croen EC, Zaveri K, Ratner L
Int J Colorectal Dis. 2002 May; 17(3): 156-60
READ MORECarcinoid Tumors: Molecular genetics, tumor biology, and update of diagnosis and treatment
Article by Oberg Kjell M.D.
Department of Medical Sciences, Uppsala University Hospital,
Uppsala, Sweden.
Current Opinion Oncology. 2002 Jan; 14(1): 38-45
READ MOREYear 2001
Experience in treatment of metastatic pulmonary carcinoid tumors
Granberg D, Eriksson B, Wilander E, Grimfjärd P, Fjällskog M-L, Öberg K, Skogseid B. Experience in treatment of metastatic pulmonary carcinoid tumors.
Ann Oncol. 2001; 12(10): 1383-1391
READ MORELung and thymic neuroendocrine tumors
Granberg D, Skogseid B
Doherty G, Skogseid B, eds. Surgical Endocrinology. Philadelphia. Lippincott Williams & Wilkins.. 2001: 413-430
READ MOREYear 2000
Carcinoid and Pancreatic Endocrine Tumors: Recent advances in molecular pathogenesis, localization, and treatment
Jensen, RT
Curr Opin Oncol. 2000 Jul; 12(4): 368-77
READ MOREMiscellaneous
Information on Carcinoid and Related Neuroendocrine Tumors
Several authors- collection of webpages
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